Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17956922 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTKMT2ALMNANMBR | |
| SCHEMBL17957087 | 0.73 | SMN1; SMN2 (0.51) | TP53SMN1; SMN2EPHX1NFKB1EPHX2 | |
| SCHEMBL17957009 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMEN1KMT2ALMNA | |
| SCHEMBL17956934 | 0.69 | NPSR1 (0.46) | SMN1; SMN2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL18137772 | 0.69 | NPSR1 (0.45) | SMN1; SMN2MAPTNPC1MEN1KMT2A | |
| SCHEMBL17957011 | 0.69 | KMT2A (0.45) | POLBMEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL17957057 | 0.68 | KMT2A (0.46) | TP53SMN1; SMN2MAPTPOLBRXFP1 | |
| SCHEMBL17956921 | 0.68 | KDM4E (0.44) | SMN1; SMN2MAPTPOLBLMNANMBR | |
| SCHEMBL7250903 | 0.68 | TSHR (0.46) | SMN1; SMN2EPHX1MAPTNPC1RAB9A | |
| SCHEMBL17957086 | 0.68 | POLB (0.51) | SMN1; SMN2TDP1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050871-B1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR) | 2018-11-07 | — | — | EP | disclosed |
| US-10064843-B2 | Bis-amide derivative and use thereof | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2018-09-04 | — | — | US | disclosed |
| US-20160297751-A1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2016-10-13 | — | — | US | disclosed |
| EP-3050871-A1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | University-Industry Cooperation Group of Kyung Hee University (KR) | 2016-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10064843-B2 | Bis-amide derivative and use thereof | CYP2C8, CYP4F8, CYP2F1 | STING1 131/4885TP53 1440/4885SMN1; SMN2 4861/4885 |
| US-20160297751-A1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | CYP2C8, CYP4F8, CYP2F1 | STING1 96/4885TP53 1575/4885SMN1; SMN2 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.