Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590394 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL8491759 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2HSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL13176906 | 0.72 | NPC1 (0.31) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9879229 | 0.69 | KMT2A (0.32) | SMN1; SMN2KMT2A | |
| SCHEMBL857098 | 0.67 | KMT2A (0.46) | SMN1; SMN2KMT2AMEN1ALDH1A1HTR2A | |
| SCHEMBL14183605 | 0.66 | HTR2A (0.35) | KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL7389179 | 0.64 | TNKS (0.33) | — | |
| SCHEMBL22574603 | 0.64 | KMT2A (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL28960187 | 0.62 | KMT2A (0.37) | KMT2AMEN1ALDH1A1POLBHTR2A | |
| SCHEMBL75623 | 0.62 | PDE10A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510517-A | Preparation method of PDE4B inhibitor BI-1015550 | 云南万宏医药科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117510517-A | Preparation method of PDE4B inhibitor BI-1015550 | 云南万宏医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2016119707-A1 | NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016119707-A1 | NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-08-04 | — | — | WO | disclosed |