Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.79 |
| ▸ | ABL1 | P00519 | 12/20 | 0.79 |
| ▸ | HCK | P08631 | 2/20 | 0.69 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.68 |
| ▸ | CSK | P41240 | 1/20 | 0.68 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.66 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.66 |
| ▸ | PRKDC | P78527 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14574642 | 0.88 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL29389616 | 0.88 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL12436041 | 0.88 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL29390202 | 0.88 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL14574791 | 0.85 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL29391145 | 0.85 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL14574643 | 0.84 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL29389641 | 0.84 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL14574634 | 0.82 | SRC (1.00) | SRCABL1HCKEGFRLCK | |
| SCHEMBL29387857 | 0.82 | SRC (1.00) | SRCABL1HCKEGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250290-A1 | COMPOSITIONS AND METHODS FOR TREATING TOXOPLASMOSIS, CRYPTOSPORIDIOSIS AND OTHER APICOMPLEXAN PROTOZOAN RELATED DISEASES | University of Washington (US) | 2017-12-06 | — | — | EP | claimed |
| WO-2016123152-A1 | COMPOSITIONS AND METHODS FOR TREATING TOXOPLASMOSIS, CRYPTOSPORIDIOSIS AND OTHER APICOMPLEXAN PROTOZOAN RELATED DISEASES | UNIVERSITY OF WASHINGTON (US) | 2016-08-04 | — | — | WO | claimed |