Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 20/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17964592 | 1.00 | PI4KB (0.65) | PI4KBKCNH2 | |
| SCHEMBL17964593 | 1.00 | PI4KB (0.65) | PI4KBKCNH2 | |
| SCHEMBL17964786 | 0.89 | PI4KB (0.67) | PI4KBKCNH2 | |
| SCHEMBL17964979 | 0.89 | PI4KB (0.51) | PI4KBKCNH2 | |
| SCHEMBL17964696 | 0.89 | PI4KB (0.65) | PI4KBKCNH2 | |
| SCHEMBL17964665 | 0.88 | PI4KB (0.78) | PI4KBKCNH2 | |
| SCHEMBL17964668 | 0.88 | PI4KB (0.78) | PI4KBKCNH2 | |
| SCHEMBL17964965 | 0.86 | PI4KB (0.63) | PI4KBKCNH2 | |
| SCHEMBL17964730 | 0.86 | PI4KB (0.61) | PI4KBKCNH2 | |
| SCHEMBL17964796 | 0.85 | PI4KB (0.61) | PI4KBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776445-B1 | THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-10 | — | — | EP | claimed |
| EP-2776445-B1 | THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-10 | — | — | EP | disclosed |