Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 20/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965011 | 1.00 | PI4KB (0.60) | PI4KBKCNH2 | |
| SCHEMBL17964652 | 0.89 | PI4KB (0.61) | PI4KBKCNH2 | |
| SCHEMBL17964651 | 0.89 | PI4KB (0.61) | PI4KBKCNH2 | |
| SCHEMBL17964924 | 0.87 | PI4KB (0.51) | PI4KBKCNH2 | |
| SCHEMBL17964675 | 0.85 | PI4KB (0.63) | PI4KBKCNH2 | |
| SCHEMBL17964676 | 0.85 | PI4KB (0.63) | PI4KBKCNH2 | |
| SCHEMBL17964764 | 0.84 | PI4KB (0.64) | PI4KBKCNH2 | |
| SCHEMBL17964762 | 0.84 | PI4KB (0.64) | PI4KBKCNH2 | |
| SCHEMBL17964559 | 0.82 | PI4KB (0.61) | PI4KBKCNH2 | |
| SCHEMBL17964557 | 0.82 | PI4KB (0.61) | PI4KBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776445-B1 | THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-10 | — | — | EP | claimed |
| EP-2776445-B1 | THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-10 | — | — | EP | disclosed |