SCHEMBL17967697

SCHEMBL17967697

COCc1cc2[nH]c3nc(-c4cnn(C)c4)ccc3c2cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17967694 0.88 MAPT (0.85) MAPT
SCHEMBL17967563 0.83 MAPT (1.00) MAPT
SCHEMBL17967602 0.82 MAPT (0.70) MAPT
SCHEMBL17967657 0.82 MAPT (1.00) MAPT
SCHEMBL17967692 0.81 MAPT (1.00) MAPT
SCHEMBL17967666 0.81 MAPT (1.00) MAPT
SCHEMBL17967661 0.77 MAPT (0.63) MAPT
SCHEMBL17967607 0.75 MAPT (1.00) MAPT
SCHEMBL17967605 0.72 MAPT (1.00) MAPT
SCHEMBL17967628 0.70 MAPT (0.83) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253762-B1 9H-PYRROLO-DIPYRIDINE DERIVATIVES UCB Biopharma SRL (BE) 2021-05-05 EP claimed
EP-3253762-B1 9H-PYRROLO-DIPYRIDINE DERIVATIVES UCB Biopharma SRL (BE) 2021-05-05 EP disclosed
WO-2016124508-A1 9H-PYRROLO-DIPYRIDINE DERIVATIVES UCB BIOPHARMA SPRL (BE) 2016-08-11 WO disclosed