Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.67 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.67 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.67 |
| ▸ | SRC | P12931 | 9/20 | 0.49 |
| ▸ | KDR | P35968 | 9/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.49 |
| ▸ | ABL1 | P00519 | 8/20 | 0.49 |
| ▸ | EGFR | P00533 | 8/20 | 0.49 |
| ▸ | HCK | P08631 | 8/20 | 0.49 |
| ▸ | MTOR | P42345 | 8/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 8/20 | 0.49 |
| ▸ | PRKDC | P78527 | 8/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | STK16 | O75716 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651776 | 0.97 | PIK3CD (0.71) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL11793 | 0.97 | PIK3CD (0.71) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL131081 | 0.94 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL15582861 | 0.94 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL29651637 | 0.94 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL10790 | 0.94 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL12322 | 0.92 | PIK3CD (0.64) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL29651826 | 0.92 | PIK3CD (0.64) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL13828404 | 0.91 | PIK3CD (0.64) | PIK3CDPIK3CGCSNK1EPIK3R1SRC | |
| SCHEMBL13828398 | 0.91 | PIK3CD (0.64) | PIK3CDPIK3CGCSNK1EPIK3R1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050876-A2 | KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2016-08-03 | — | — | EP | disclosed |