⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4326259 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6507476 | 0.97 | — | — | |
| Bromide SCHEMBL28748013 | 0.97 | — | — | |
| SCHEMBL28172221 | 0.92 | — | — | |
| SCHEMBL28166931 | 0.69 | — | — | |
| SCHEMBL28267747 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28176836 | 0.67 | — | — | |
| SCHEMBL446759 | 0.67 | — | — | |
| SCHEMBL3851809 | 0.65 | — | — | |
| SCHEMBL1867697 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768423-A | Inhibitors of EGFR, KRAS, BRAF and other targets and uses thereof | 密歇根大学董事会 | 2023-03-07 | — | — | CN | claimed |
| EP-3440067-B1 | TETRAHYDROISOQUINOLINE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2021-05-26 | — | — | EP | claimed |
| CN-105051032-B | Antibody connexon drug conjugates, its preparation method and the anticancer pharmaceutical composition comprising it | 赛特瑞恩股份有限公司 | 2017-08-15 | — | — | CN | claimed |
| EP-1904483-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. Hoffmann-Roche AG (CH) | 2008-04-02 | — | — | EP | claimed |
| CN-1326838-C | Benzo[d]azepine derivatives for the treatment of neurological disorders | GLAXO GROUP LTD (GB) | 2007-07-18 | — | — | CN | claimed |
| WO-2007006677-A1 | BENZIMIDAZOLE DERIVATIVES AS 5-HT6,5-HT24 | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-18 | — | — | WO | claimed |
| US-20070015744-A1 | Benzimidazolone and dihydroindolone derivatives and uses thereof | ROCHE PALO ALTO LLC | 2007-01-18 | — | — | US | claimed |
| EP-1713790-A2 | METHOD OF PREPARATION OF BENZOFURAN-2-CARBOXYLIC ACID (S)-3-METHYL-1- ((4S, 7R)-7METHYL-3-OXO-1-(PYRIDINE-2-SULFONYL)-AZ EPAN-4-YLCARBAMOYL-BUTYL)-AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-25 | — | — | EP | claimed |
| WO-2005069981-A2 | METHOD OF PREPARATION OF BENZOFURAN-2-CARBOXYLIC ACID {(S)-3-METHYL-1-[(4S, 7R)-7METHYL-3-OXO-1-(PYRIDINE-2-SULFONYL)-AZEPAN-4-YLCARBAMOYL]-BUTYL}-AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-04 | — | — | WO | claimed |
| WO-2005042491-A1 | BENZAZEPINE DERIVATIVES AND METHODS OF PROPHYLAXIS OR TREATMENT OF 5HT2C RECEPTOR ASSOCIATED DISEASES | ARENA PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| CN-119570825-A | Method for efficiently synthesizing protoberberine compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2025-03-07 | — | — | CN | disclosed |
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115768423-A | Inhibitors of EGFR, KRAS, BRAF and other targets and uses thereof | 密歇根大学董事会 | 2023-03-07 | — | — | CN | disclosed |
| CN-115047104-A | Method for rapidly detecting illegal addition of 36 antihistamines in cosmetics | 重庆市食品药品检验检测研究院 | 2022-09-13 | — | — | CN | disclosed |
| US-20220017433-A1 | PHOTOCHEMICALLY INDUCED CONJUGATION OF RADIOMETALS TO SMALL MOLECULES, PEPTIDES AND NANOPARTICLES IN A SIMULTANEOUS ONE-POT REACTION | Universität Zürich (CH) | 2022-01-20 | — | — | US | disclosed |
| US-5580979-A | Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions | TRUSTEES OF TUFTS UNIVERSITY (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1995025118-A2 | INHIBITORS OF SH2 DOMAIN INTERACTIONS | TRUSTEES OF TUFTS UNIVERSITY (US) | 1995-09-21 | — | — | WO | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |
| CN-1035724-A | Photosensitive silve halide material | FUJI PHOTO FILM CO LTD (JP) | 1989-09-20 | — | — | CN | disclosed |