Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.61 |
| ▸ | MAOB | P27338 | 9/20 | 0.57 |
| ▸ | HTR2B | P41595 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18016880 | 0.81 | HTR2C (0.58) | HTR2CHTR2BHTR2ADRD2DRD4 | |
| SCHEMBL18016892 | 0.81 | HTR2C (0.59) | HTR2CHTR2BHTR2ADRD2DRD4 | |
| SCHEMBL24434865 | 0.81 | HTR2C (0.41) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL18016878 | 0.81 | HTR2C (0.58) | HTR2CHTR2BHTR2ADRD2DRD4 | |
| SCHEMBL18016867 | 0.81 | HTR2C (0.59) | HTR2CHTR2BHTR2ADRD2DRD4 | |
| SCHEMBL18016885 | 0.78 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL15415942 | 0.77 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL22335039 | 0.74 | HTR2C (0.55) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL1798792 | 0.74 | HTR2C (0.46) | HTR2CHTR2BHTR2ASLC6A2SLC6A3 | |
| SCHEMBL18016883 | 0.74 | HTR2C (0.60) | HTR2CHTR2BHTR2AKDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951752-B2 | O-cyclopropyl-carboxanilides and their use as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-31 | — | — | US | disclosed |
| US-20090197925-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| EP-1829865-A2 | Chemical compounds | Syngeta Participations AG (CH) | 2007-09-05 | — | — | EP | disclosed |
| EP-1480955-B1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-27 | — | — | EP | disclosed |
| CN-1293058-C | O-cyclopropyl-carboxanilides and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-03 | — | — | CN | disclosed |
| US-20050221989-A1 | O-cyclopropyl-carboxanilides and their use as fungicides | SYNGENTA CROP PROTECTION, INC. | 2005-10-06 | — | — | US | disclosed |
| CN-1639128-A | O-cyclopropyl-carboxanilides and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-13 | — | — | CN | disclosed |
| EP-1480955-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074491-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050221989-A1 | O-cyclopropyl-carboxanilides and their use as fungicides | CBR3, CBR1, CYP2E1 | HTR2C 844/4885MAOB 1222/4885HTR2B 792/4885 |
| US-20090197925-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE | CBR3, CBR1, CYC1 | HTR2C 971/4885MAOB 1726/4885HTR2B 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.