Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | SCN4A | P35499 | 4/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172487 | 1.00 | AOC3 (0.45) | AOC3ACHESLC6A4ACP3TAAR1 | |
| SCHEMBL5712566 | 0.87 | SLC6A4 (0.48) | SLC6A4SCN4AANPEPENPEP | |
| SCHEMBL28337687 | 0.84 | AOC3 (0.42) | AOC3ACHESLC6A4ACP3TAAR1 | |
| SCHEMBL12056788 | 0.84 | AOC3 (0.42) | AOC3ACHESLC6A4ACP3TAAR1 | |
| SCHEMBL28337706 | 0.84 | AOC3 (0.42) | AOC3ACHESLC6A4ACP3TAAR1 | |
| SCHEMBL4277230 | 0.83 | AOC3 (0.45) | AOC3ACHEACP3TAAR1TACR1 | |
| SCHEMBL30559594 | 0.82 | AOC3 (0.44) | AOC3ACHEACP3TAAR1TACR1 | |
| SCHEMBL4598026 | 0.82 | AOC3 (0.44) | AOC3ACHEACP3TAAR1TACR1 | |
| SCHEMBL20274525 | 0.82 | TAAR1 (0.47) | AOC3ACHEACP3TAAR1TACR1 | |
| SCHEMBL18765644 | 0.82 | AOC3 (0.44) | AOC3ACHEACP3TAAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2016131789-A1 | BENZOPYRROLIDONE DERIVATIVES POSSESSING ANTIVIRAL AND ANTICANCER PROPERTIES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-08-25 | — | — | WO | disclosed |
| EP-3056202-A1 | BENZOPYRROLIDONE DERIVATIVES POSSESSING ANTIVIRAL AND ANTICANCER PROPERTIES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-08-17 | — | — | EP | disclosed |