Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 12/20 | 0.80 |
| ▸ | GCGR | P47871 | 10/20 | 0.76 |
| ▸ | GLP1R | P43220 | 2/20 | 0.76 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.76 |
| ▸ | GIPR | P48546 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11962749 | 0.89 | GCG (1.00) | GCGGCGRGLP1RCHRM5GIPR | |
| SCHEMBL11962691 | 0.87 | GCGR (0.76) | GCGGCGRGLP1RGIPR | |
| SCHEMBL11962739 | 0.87 | GCG (1.00) | GCGGCGRGLP1RCHRM5 | |
| Pf-06291874 SCHEMBL11901097 | 0.86 | GCGR (1.00) | GCGGCGRGLP1RCHRM5GIPR | |
| Pf-06291874 SCHEMBL11899337 | 0.86 | GCGR (1.00) | GCGGCGRGLP1RCHRM5GIPR | |
| Pf-06291874 SCHEMBL11900272 | 0.86 | GCGR (1.00) | GCGGCGRGLP1RCHRM5GIPR | |
| SCHEMBL11899682 | 0.81 | GCG (1.00) | GCGGCGRGLP1RCHRM5 | |
| SCHEMBL11899686 | 0.81 | GCG (1.00) | GCGGCGRGLP1RCHRM5 | |
| SCHEMBL16310832 | 0.81 | GCGR (0.80) | GCGGCGRGLP1RCHRM5 | |
| SCHEMBL11899926 | 0.81 | GCG (1.00) | GCGGCGRGLP1RCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673260-B1 | GLUCAGON RECEPTOR MODULATOR | PFIZER (US) | 2016-08-17 | — | — | EP | disclosed |