Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15003143 | 0.92 | CSNK1E (0.36) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL12055826 | 0.88 | CSNK1E (0.44) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL14994792 | 0.87 | CSNK1E (0.48) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL24339526 | 0.84 | CSNK1E (0.39) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL29020895 | 0.84 | CSNK1E (0.39) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL18641633 | 0.84 | CSNK1E (0.39) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL18665359 | 0.84 | CSNK1E (0.39) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL14372493 | 0.82 | SGPL1 (0.43) | CSNK1EPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL17972405 | 0.82 | PRSS1 (0.39) | CSNK1EALDH1A1PRSS1CTSGCTRB1 | |
| SCHEMBL12261534 | 0.82 | CSNK1E (0.36) | CSNK1EALDH1A1PRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220595-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220595-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | PNP, NTPCR, TYMP | CSNK1E 3730/4885ALDH1A1 1897/4885PRSS1 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.