Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 4/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
| ▸ | RPA1 | P27694 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17977311 | 0.89 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL17977359 | 0.89 | MYC (0.37) | CHRNA7MYCNR4A1ESR1ESR2 | |
| SCHEMBL17977349 | 0.89 | MYC (0.34) | CHRNA7MYCNR4A1ESR1HCAR2 | |
| SCHEMBL17977477 | 0.86 | STING1 (0.39) | MYCNR4A1MAPTSMN1; SMN2 | |
| SCHEMBL17977476 | 0.85 | NOTUM (0.37) | ESR1ESR2RPA1 | |
| SCHEMBL17977356 | 0.83 | ESR1 (0.35) | ESR1ESR2RPA1 | |
| SCHEMBL17977351 | 0.77 | ESR1 (0.36) | MYCESR1ESR2 | |
| SCHEMBL17977471 | 0.76 | MYC (0.34) | MYC | |
| SCHEMBL17977305 | 0.76 | AR (0.33) | ESR1ESR2 | |
| SCHEMBL18019380 | 0.75 | AR (0.38) | CHRNA7MYCNR4A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128905-A1 | THIENOPYRROLE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-08-18 | — | — | WO | claimed |