Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.67 |
| ▸ | PDE6C | P51160 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | PDE1A | P54750 | 2/20 | 0.66 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.66 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.62 |
| ▸ | PDE2A | O00408 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17390153 | 0.93 | PDE5A (0.73) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL17980848 | 0.90 | PDE5A (0.76) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL18714950 | 0.90 | PDE5A (0.74) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL16003753 | 0.88 | PDE5A (0.89) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL16003676 | 0.88 | PDE5A (0.89) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL16003761 | 0.88 | PDE5A (0.89) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL16003783 | 0.88 | PDE5A (0.89) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL17390102 | 0.88 | PDE5A (0.84) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL18715295 | 0.88 | PDE5A (0.70) | PDE5AHDAC6HDAC1PDE3AHDAC2 | |
| SCHEMBL16003653 | 0.88 | PDE5A (0.77) | PDE5AHDAC6HDAC1PDE3AHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016120432-A1 | COMPOUNDS AND METHODS FOR ANTICOAGULATION THERAPY | FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA (ES) | 2016-08-04 | — | — | WO | disclosed |