Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17987566 | 0.90 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL17956620 | 0.88 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL17987643 | 0.78 | NR3C2 (0.34) | KCNH2 | |
| SCHEMBL17956631 | 0.77 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL17987562 | 0.77 | PCSK9 (0.41) | KCNH2 | |
| SCHEMBL3271883 | 0.76 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL17970284 | 0.73 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL15845113 | 0.73 | NR3C2 (0.46) | — | |
| SCHEMBL17970295 | 0.71 | AAK1 (0.33) | — | |
| SCHEMBL4296620 | 0.71 | GAA (0.37) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016123146-A1 | BRIDGED COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | MERCK SHARP & DOHME CORP. (US) | 2016-08-04 | — | — | WO | disclosed |