Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 4/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 7/20 | 0.42 |
| ▸ | CHAT | P28329 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083493 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16288778 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16288783 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16288769 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16574820 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16288774 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16288767 | 0.96 | EP300 (0.47) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL23157246 | 0.91 | DOT1L (0.46) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16289546 | 0.91 | DOT1L (0.46) | EP300KAT5CREBBPRNASELCHAT | |
| SCHEMBL16289533 | 0.91 | DOT1L (0.46) | EP300KAT5CREBBPRNASELCHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |