Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996777 | 0.92 | KDM4E (0.48) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL19380387 | 0.91 | KDM4E (0.47) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL5001588 | 0.69 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL2182908 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL22063216 | 0.67 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL26078910 | 0.67 | CHEK1 (0.53) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL18117335 | 0.66 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL20821353 | 0.66 | KDM4E (0.47) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL2163340 | 0.66 | ADORA2A (0.45) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL15579203 | 0.66 | KDM4E (0.56) | KDM4EALDH1A1GAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054498-B1 | BISIMIDAZODIAZOCINES | IDEMITSU KOSAN CO (JP) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016125110-A1 | BISIMIDAZOLODIAZOCINES | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-11 | — | — | WO | disclosed |
| EP-3054498-A1 | Bisimidazodiazocines | Idemitsu Kosan Co., Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |