Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184368 | 0.91 | TRPV1 (0.77) | TRPV1 | |
| SCHEMBL4344253 | 0.91 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL4192780 | 0.90 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL5633821 | 0.90 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL5632806 | 0.87 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL5633139 | 0.87 | TRPV1 (0.77) | TRPV1 | |
| SCHEMBL5632546 | 0.85 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4196015 | 0.85 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL4184985 | 0.85 | TRPV1 (0.86) | TRPV1 | |
| SCHEMBL5634137 | 0.84 | TRPV1 (0.85) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422293-B2 | Tetrahydro-pyrimidoazepines as modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2016-08-23 | — | — | US | disclosed |