Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 16/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368599 | 0.86 | BCHE (0.44) | BCHE | |
| SCHEMBL20216104 | 0.83 | BCHE (0.46) | BCHEALDH1A1 | |
| SCHEMBL17518574 | 0.81 | BCHE (0.40) | BCHEKLK7KLK5 | |
| SCHEMBL7276665 | 0.81 | BCHE (0.54) | BCHEALDH1A1 | |
| SCHEMBL7150802 | 0.81 | BCHE (0.54) | BCHEALDH1A1 | |
| SCHEMBL16200950 | 0.81 | BCHE (0.54) | BCHEALDH1A1 | |
| SCHEMBL7152562 | 0.81 | BCHE (0.54) | BCHEALDH1A1 | |
| SCHEMBL12199932 | 0.81 | BCHE (0.54) | BCHEALDH1A1 | |
| SCHEMBL13972170 | 0.81 | BCHE (0.54) | BCHEALDH1A1 | |
| SCHEMBL29337144 | 0.78 | BCHE (0.47) | BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988393-B2 | Isosorbide-based polymethacrylates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-06-05 | — | — | US | disclosed |
| US-20160229863-A1 | ISOSORBIDE-BASED POLYMETHACRYLATES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2016-08-11 | — | — | US | disclosed |
| US-20160229863-A1 | ISOSORBIDE-BASED POLYMETHACRYLATES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229863-A1 | ISOSORBIDE-BASED POLYMETHACRYLATES | AKR1C4, AKR1C3, AKR1C2 | BCHE 1284/4885ALDH1A1 430/4885KLK7 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.