SCHEMBL17999909

SCHEMBL17999909

c1ccc(N(c2ccc3c(c2)Oc2cccc4c(N(c5ccccc5)c5ccccc5)ccc-3c24)c2ccc3ccccc3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
TYMS P04818 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16282081 1.00 KDM4E (0.38) KDM4EMAPK1ATMMEN1POLB
SCHEMBL16282049 1.00 KDM4E (0.38) KDM4EMAPK1ATMMEN1POLB
SCHEMBL17999969 0.93 KDM4E (0.35) KDM4EMAPK1ATM
SCHEMBL16282051 0.93 KDM4E (0.37) KDM4EMAPK1ATMMEN1POLB
SCHEMBL16282074 0.93 KDM4E (0.33) KDM4EMAPK1ATM
SCHEMBL17999954 0.92 KDM4E (0.35) KDM4EMAPK1ATM
SCHEMBL17999942 0.92 KDM4E (0.38) KDM4EMAPK1ATM
SCHEMBL17999914 0.92 KDM4E (0.38) KDM4EMAPK1ATM
SCHEMBL17999946 0.92 KDM4E (0.34) KDM4EMAPK1ATM
SCHEMBL25915638 0.91 KDM4E (0.35) KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160233428-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-11 US disclosed
US-20160233428-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-11 US disclosed