Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 19/20 | 0.56 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185722 | 0.86 | CCR4 (0.54) | CCR4 | |
| SCHEMBL185508 | 0.83 | CCR4 (0.60) | CCR4ABHD6 | |
| SCHEMBL17876 | 0.83 | BUB1 (0.47) | CCR4 | |
| SCHEMBL27431 | 0.83 | CCR4 (0.47) | CCR4 | |
| SCHEMBL186393 | 0.82 | CSF1R (0.47) | CCR4 | |
| SCHEMBL27571 | 0.82 | CCR4 (0.62) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL22678941 | 0.79 | CCR4 (0.66) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30708 | 0.78 | CCR4 (0.59) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL21896 | 0.77 | CCR4 (0.71) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL185970 | 0.77 | CCR4 (0.52) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |