Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801261 | 1.00 | S1PR1 (0.54) | S1PR1S1PR3 | |
| SCHEMBL1801260 | 1.00 | S1PR1 (0.54) | S1PR1S1PR3 | |
| SCHEMBL1802090 | 0.92 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL1800716 | 0.91 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL1799074 | 0.89 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL1799072 | 0.89 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL1799070 | 0.89 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL1800494 | 0.89 | S1PR1 (0.55) | S1PR1S1PR3 | |
| SCHEMBL1800493 | 0.89 | S1PR1 (0.55) | S1PR1S1PR3 | |
| SCHEMBL1800496 | 0.89 | S1PR1 (0.55) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951794-B2 | Thiophene derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-05-31 | — | — | US | disclosed |
| EP-1896446-A1 | NOVEL THIOPHENE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006137019-A1 | NOVEL THIOPHENE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2006-12-28 | — | — | WO | disclosed |