Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19779316 | 1.00 | PDE8B (0.43) | PDE8BALOX5APFEN1KDM1AATM | |
| SCHEMBL18015127 | 1.00 | PDE8B (0.43) | PDE8BALOX5APFEN1KDM1AATM | |
| SCHEMBL18015118 | 0.96 | ALOX5AP (0.45) | PDE8BALOX5APFEN1ATMALDH1A1 | |
| SCHEMBL18015133 | 0.96 | ALOX5AP (0.45) | PDE8BALOX5APFEN1ATMALDH1A1 | |
| SCHEMBL18015115 | 0.96 | ALOX5AP (0.45) | PDE8BALOX5APFEN1ATMALDH1A1 | |
| SCHEMBL19768833 | 0.91 | PDE8B (0.42) | PDE8BALOX5APFEN1KDM1AATM | |
| SCHEMBL19768838 | 0.91 | PDE8B (0.42) | PDE8BALOX5APFEN1KDM1AATM | |
| SCHEMBL18015116 | 0.90 | ALOX5AP (0.38) | ALOX5APFEN1ATMALDH1A1HSD17B10 | |
| SCHEMBL24760647 | 0.85 | HPGD (0.44) | PDE8BALOX5APFEN1KDM1AATM | |
| SCHEMBL18015119 | 0.84 | ATM (0.43) | PDE8BALOX5APFEN1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016123707-A1 | PROCESS FOR THE SYNTHESIS OF DIFLUOROMETHYL ETHER-BASED COMPOUNDS | TRILLIUM THERAPEUTICS INC. (CA) | 2016-08-11 | — | — | WO | disclosed |