SCHEMBL1801566

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1797864	0.90	TRPV1 (0.54)	TRPV1HTR2BHCRTR1HCRTR2TRPA1
	SCHEMBL12350627	0.89	TRPV1 (0.42)	TRPV1ROCK2HCRTR1HCRTR2PDE10A
	SCHEMBL12350618	0.89	TRPV1 (0.42)	TRPV1ROCK2HCRTR1HCRTR2PDE10A
	SCHEMBL12350621	0.89	TRPV1 (0.42)	TRPV1ROCK2HCRTR1HCRTR2PDE10A
	SCHEMBL12350625	0.89	TRPV1 (0.42)	TRPV1ROCK2HCRTR1HCRTR2PDE10A
	SCHEMBL12350594	0.89	TRPV1 (0.42)	TRPV1ROCK2HCRTR1HCRTR2PDE10A
	SCHEMBL1797611	0.89	TRPV1 (0.50)	TRPV1ROCK1HCRTR1HCRTR2PDE10A
	SCHEMBL1795829	0.88	TRPV1 (0.42)	TRPV1HTR2BHCRTR1HCRTR2PDE10A
	SCHEMBL12350215	0.88	TRPV1 (0.42)	TRPV1HTR2BPDE10ATRPA1
	SCHEMBL1797448	0.88	TRPV1 (0.42)	TRPV1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.