SCHEMBL18017879

SCHEMBL18017879

c1ccc(-c2nc(-c3ccc(-c4nc(-c5ccccc5)nc5oc6ccccc6c45)cc3)c3c(n2)oc2ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ ATM Q13315 1/20 0.45
▸ MAPT P10636 5/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ CSF1R P07333 1/20 0.41
▸ PDGFRB P09619 1/20 0.41
▸ KIT P10721 1/20 0.41
▸ FLT3 P36888 1/20 0.41
▸ HDAC6 Q9UBN7 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ WHR1 P49842 1/20 0.39
▸ LMNA P02545 2/20 0.38
▸ ADK P55263 2/20 0.38
▸ ALDH1A1 P00352 5/20 0.38
▸ HPGD P15428 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18017783 1.00 MEN1 (0.45) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18017923 1.00 MEN1 (0.45) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18017780 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18018392 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL16902564 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18018359 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18017797 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL16902590 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18017880 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2
SCHEMBL18370598 0.98 KMT2A (0.44) MEN1KMT2AATMMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 — — US disclosed
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OCIAD1 MEN1 3118/4885KMT2A 4272/4885ATM 4280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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