SCHEMBL18018037

SCHEMBL18018037

c1ccc(-c2ccc(-c3nc(-c4ccccc4-c4ccccc4-c4ccccc4-c4nc(-c5ccc(-c6ccccc6)cc5)c5oc6ccccc6c5n4)nc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.47
▸ ALDH1A1 P00352 8/20 0.46
▸ TSHR P16473 5/20 0.46
▸ KDM4E B2RXH2 4/20 0.46
▸ POLB P06746 3/20 0.46
▸ HPGD P15428 2/20 0.46
▸ NPSR1 Q6W5P4 3/20 0.45
▸ KMT2A Q03164 7/20 0.44
▸ MEN1 O00255 6/20 0.44
▸ LMNA P02545 5/20 0.44
▸ HSD17B10 Q99714 3/20 0.44
▸ USP2 O75604 1/20 0.44
▸ CSF1R P07333 1/20 0.44
▸ PDGFRB P09619 1/20 0.44
▸ KIT P10721 1/20 0.44
▸ FLT3 P36888 1/20 0.44
▸ HDAC6 Q9UBN7 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ ADORA2A P29274 1/20 0.43
▸ MAPK1 P28482 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18018034 1.00 MAPT (0.47) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018031 0.99 MAPT (0.48) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018006 0.97 MAPT (0.49) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018263 0.97 MAPT (0.49) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL16902231 0.96 MAPT (0.49) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018021 0.96 MAPT (0.50) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018030 0.95 MAPT (0.49) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018040 0.95 MAPT (0.49) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18018028 0.93 MAPT (0.50) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL16902175 0.93 MAPT (0.51) MAPTALDH1A1TSHRKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 — — US disclosed
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OCIAD1 MAPT 2194/4885ALDH1A1 63/4885TSHR 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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