Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 7/20 | 0.51 |
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PEPD | P12955 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987819 | 0.89 | XIAP (0.53) | KMT2AL3MBTL1XIAP | |
| SCHEMBL3265348 | 0.89 | XIAP (0.53) | KMT2AL3MBTL1XIAP | |
| SCHEMBL10404192 | 0.88 | CMA1 (0.53) | KMT2AL3MBTL1ACERENKDM4E | |
| SCHEMBL5280818 | 0.88 | CMA1 (0.53) | KMT2AL3MBTL1ACERENKDM4E | |
| SCHEMBL10404191 | 0.88 | CMA1 (0.53) | KMT2AL3MBTL1ACERENKDM4E | |
| SCHEMBL15821242 | 0.88 | ACE (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL12404590 | 0.88 | XIAP (0.49) | KMT2AL3MBTL1XIAP | |
| SCHEMBL3265303 | 0.88 | XIAP (0.49) | KMT2AL3MBTL1XIAP | |
| SCHEMBL12567110 | 0.87 | ACE (0.52) | KMT2AACERENKDM4EF2 | |
| SCHEMBL239406 | 0.87 | ACE (0.52) | KMT2AACERENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416139-B2 | Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-16 | — | — | US | disclosed |
| US-9416139-B2 | Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-16 | — | — | US | disclosed |