Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092698 | 0.90 | SIRT2 (0.42) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL16523881 | 0.90 | MAP4K4 (0.40) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL16523880 | 0.90 | MAP4K4 (0.40) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL16092696 | 0.89 | SIRT2 (0.41) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL16092605 | 0.89 | SIRT2 (0.41) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL18018803 | 0.88 | SIRT2 (0.43) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL16092594 | 0.88 | MAP4K4 (0.41) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL17779810 | 0.88 | SIRT2 (0.39) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL18383212 | 0.86 | SIRT2 (0.48) | SIRT2SIRT1CNR1KDM4EMEN1 | |
| SCHEMBL18015899 | 0.86 | SIRT2 (0.45) | SIRT2SIRT1CNR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9419225-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-08-16 | — | — | US | disclosed |