Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 9/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245027 | 0.88 | TSHR (0.39) | LMNATSHRFAAHMGLLALDH1A1 | |
| SCHEMBL5485998 | 0.87 | TSHR (0.41) | TSHRTDP1FAAHMGLLALDH1A1 | |
| SCHEMBL12112394 | 0.86 | TSHR (0.41) | LMNATSHRMAPTFAAHALDH1A1 | |
| SCHEMBL672062 | 0.82 | TSHR (0.50) | TSHRHCAR2TDP1FAAHALDH1A1 | |
| SCHEMBL12715226 | 0.81 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL3748335 | 0.81 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5486001 | 0.79 | TSHR (0.41) | LMNATSHRMAPTTDP1FAAH | |
| SCHEMBL28244507 | 0.79 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28245102 | 0.78 | TSHR (0.37) | LMNATSHRMAPTFAAHMGLL | |
| SCHEMBL552060 | 0.77 | TSHR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016131001-A1 | PROCESS AND SYSTEM FOR PRODUCTION OF POLYPROPIOLACTONE | NOVOMER INC. (US) | 2016-08-18 | — | — | WO | disclosed |