Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851234 | 1.00 | USP2 (0.53) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL28848149 | 1.00 | USP2 (0.53) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL12582706 | 0.98 | USP2 (0.50) | USP2HTTSPHK1LPAR1LPAR3 | |
| Ether SCHEMBL23852175 | 0.94 | USP2 (0.48) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL2628460 | 0.93 | HTT (0.48) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL8584886 | 0.93 | HTT (0.48) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL17126850 | 0.93 | USP2 (0.43) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL18290924 | 0.91 | TSHR (0.44) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL26803302 | 0.91 | USP2 (0.57) | USP2HTTSPHK1LPAR1LPAR3 | |
| SCHEMBL25865620 | 0.91 | USP2 (0.57) | USP2HTTSPHK1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2608785-B1 | LIPOMACROCYCLES AND USES THEREOF | CUI KUNYUAN (US) | 2016-08-17 | — | — | EP | disclosed |