Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.85 |
| ▸ | CCR3 | P51677 | 20/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180396 | 1.00 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL27717243 | 1.00 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL180257 | 0.93 | HRH1 (0.84) | HRH1CCR3KCNH2 | |
| SCHEMBL30397281 | 0.92 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180058 | 0.92 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180012 | 0.92 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180011 | 0.92 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| Water SCHEMBL27717183 | 0.91 | HRH1 (0.98) | HRH1CCR3KCNH2 | |
| Water SCHEMBL180418 | 0.91 | HRH1 (0.98) | HRH1CCR3KCNH2 | |
| Alcohol SCHEMBL180256 | 0.90 | HRH1 (0.97) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402316-A1 | Piperidine derivatives | AstraZeneca AB (Publ) (SE) | 2012-01-04 | — | — | EP | disclosed |
| CN-101268049-A | Novel piperidine derivatives | ASTRAZENECA AB (SE) | 2008-09-17 | — | — | CN | disclosed |