SCHEMBL18020633

SCHEMBL18020633

OC[C@H]1O[C@H](c2ccc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)s2)[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 18/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15820815 1.00 SLC5A2 (0.54) SLC5A2
SCHEMBL22373216 0.92 SLC5A2 (0.48) SLC5A2
SCHEMBL20886717 0.84 SLC5A2 (0.43) SLC5A2
SCHEMBL12426050 0.80 SLC5A2 (0.67) SLC5A2
SCHEMBL8923507 0.79 SLC5A2 (0.48) SLC5A2
SCHEMBL9215153 0.79 SLC5A2 (0.48) SLC5A2
SCHEMBL15822612 0.79 SLC5A2 (0.63) SLC5A2
SCHEMBL15822614 0.79 SLC5A2 (0.63) SLC5A2
SCHEMBL8351368 0.76 SLC5A2 (0.73) SLC5A2
SCHEMBL15682799 0.76 SLC5A2 (0.73) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160235775-A1 Mannose Derivatives for Treating Bacterial Infections VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) 2016-08-18 — — US disclosed
US-20160235775-A1 Mannose Derivatives for Treating Bacterial Infections VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) 2016-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160235775-A1 Mannose Derivatives for Treating Bacterial Infections MPI, MANBA, MAN2A1 SLC5A2 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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