Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17444983 | 0.92 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL18023409 | 0.91 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL2737589 | 0.91 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL15077276 | 0.90 | HCRTR1 (0.40) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL17445000 | 0.90 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL2737733 | 0.89 | HCRTR1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL17444981 | 0.88 | GRM5 (0.39) | KDM4E | |
| SCHEMBL15077246 | 0.88 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1 | |
| SCHEMBL15316912 | 0.88 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL15316902 | 0.88 | GRM5 (0.37) | KDM4EALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160235748-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES, INC. | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235748-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | TYMP, ZC3HAV1, TYMS | HSP90AA1 4569/4885HSP90AB1 4670/4885KDM4E 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.