Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16203978 | 0.90 | PDE4D (0.34) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL18022722 | 0.88 | PDE4D (0.37) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL430457 | 0.88 | PDE4D (0.38) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL15001754 | 0.87 | PDE4D (0.36) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL430489 | 0.85 | PDE4D (0.40) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL15001220 | 0.84 | PDE4D (0.38) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL18022717 | 0.84 | PDE4D (0.42) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL15001792 | 0.83 | PDE4D (0.37) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL18022718 | 0.83 | PDE4D (0.37) | PDE4DIKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL15001780 | 0.83 | PDE4D (0.37) | PDE4DIKBKBPRKAG1PRKAA1NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785181-B1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-08-17 | — | — | EP | disclosed |