Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475197 | 0.90 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14475209 | 0.89 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14474141 | 0.88 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14475884 | 0.87 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL16183480 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14474630 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14475164 | 0.83 | ABCG2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14475838 | 0.83 | MAPT (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL14475071 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL16183479 | 0.82 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056207-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2016-08-17 | — | — | EP | disclosed |