Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18023941 | 0.93 | MEN1 (0.53) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL18023938 | 0.91 | MEN1 (0.57) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL18023982 | 0.90 | MEN1 (0.56) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL1829876 | 0.88 | MEN1 (0.54) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL18023939 | 0.86 | MEN1 (0.53) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL18023983 | 0.85 | MEN1 (0.52) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL1767081 | 0.84 | MEN1 (0.53) | MEN1KMT2ARXFP1GFERALDH1A1 | |
| SCHEMBL1829076 | 0.83 | MEN1 (0.52) | MEN1KMT2ARXFP1ALDH1A1CSF1R | |
| SCHEMBL1766654 | 0.81 | MEN1 (0.51) | MEN1KMT2ARXFP1ALDH1A1CES1 | |
| SCHEMBL1812890 | 0.81 | MEN1 (0.48) | MEN1KMT2ARXFP1ALDH1A1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531484-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-17 | — | — | EP | disclosed |