SCHEMBL18023946

SCHEMBL18023946

NCC1OB(O)c2c(OCCO)ccc(F)c21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18023976 1.00
SCHEMBL2680122 0.94
SCHEMBL19844411 0.87
SCHEMBL19844420 0.87
SCHEMBL453354 0.86 LARS1 (0.73)
SCHEMBL453410 0.86 LARS1 (0.73)
SCHEMBL469428 0.86 LARS1 (0.73)
Trifluoroacetic Acid SCHEMBL19690261 0.85
SCHEMBL18023945 0.85 LARS1 (0.75)
Ganfeborole SCHEMBL18023952 0.85 LARS1 (0.75)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180037595-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2018-02-08 US disclosed
WO-2016128949-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2016-08-18 WO disclosed