SCHEMBL18023947

SCHEMBL18023947

CC(O)COc1ccc(I)c2c1B(O)OC2CN

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18023978 1.00 LARS1 (0.54) LARS1
SCHEMBL18023393 0.87 LARS1 (0.55) LARS1
SCHEMBL18023394 0.87 LARS1 (0.55) LARS1
SCHEMBL18023949 0.86 LARS1 (0.74) LARS1
SCHEMBL18023967 0.86 LARS1 (0.74) LARS1
SCHEMBL18023942 0.86 LARS1 (0.74) LARS1
SCHEMBL18023980 0.86 LARS1 (0.54) LARS1
SCHEMBL18023950 0.86 LARS1 (0.54) LARS1
SCHEMBL18023971 0.86 LARS1 (0.74) LARS1
SCHEMBL18023981 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180037595-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2018-02-08 US disclosed
US-20180037595-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2018-02-08 US disclosed
WO-2016128949-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2016-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037595-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF BRD3, BRPF3, BRD4 LARS1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.