SCHEMBL18023965

SCHEMBL18023965

CNC[C@H]1OB(O)c2c(OCCO)ccc(Cl)c21

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19844416 0.86 LARS1 (0.64) LARS1
SCHEMBL19844408 0.86 LARS1 (0.64) LARS1
SCHEMBL18023956 0.86 LARS1 (0.57) LARS1
SCHEMBL18023972 0.86 LARS1 (0.57) LARS1
Ganfeborole SCHEMBL18023952 0.84 LARS1 (0.75) LARS1
Ganfeborole SCHEMBL31152062 0.84 LARS1 (0.75) LARS1
Ganfeborole SCHEMBL18023955 0.84 LARS1 (0.75) LARS1
SCHEMBL18023997 0.84 LARS1 (0.55) LARS1
SCHEMBL10194654 0.83 LARS1 (0.54) LARS1
Ganfeborole SCHEMBL29880374 0.83 LARS1 (0.76) LARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016128949-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2016-08-18 WO disclosed