SCHEMBL18023979

SCHEMBL18023979

CC(C)(O)COc1ccc(F)c2c1B(O)O[C@@H]2CN

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18023948 1.00 LARS1 (0.55) LARS1
SCHEMBL19844412 0.89 LARS1 (0.44) LARS1
SCHEMBL19844406 0.89 LARS1 (0.44) LARS1
SCHEMBL18023440 0.88 LARS1 (0.55) LARS1
SCHEMBL18023960 0.87 LARS1 (0.74) LARS1
SCHEMBL18023975 0.87 LARS1 (0.54) LARS1
SCHEMBL18023957 0.87 LARS1 (0.74) LARS1
SCHEMBL18023943 0.87 LARS1 (0.74) LARS1
SCHEMBL18023951 0.87 LARS1 (0.54) LARS1
SCHEMBL469428 0.86 LARS1 (0.73) LARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180037595-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2018-02-08 US disclosed
WO-2016128949-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2016-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037595-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF BRD3, BRPF3, BRD4 LARS1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.