Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 16/20 | 0.98 |
| ▸ | LONP1 | P36776 | 11/20 | 0.98 |
| ▸ | PSMB8 | P28062 | 8/20 | 0.98 |
| ▸ | PSMB9 | P28065 | 8/20 | 0.98 |
| ▸ | PSMB6 | P28072 | 8/20 | 0.98 |
| ▸ | PSMB10 | P40306 | 8/20 | 0.98 |
| ▸ | PSMB11 | A5LHX3 | 7/20 | 0.98 |
| ▸ | PSMA7 | O14818 | 7/20 | 0.98 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.98 |
| ▸ | PSMA1 | P25786 | 7/20 | 0.98 |
| ▸ | PSMA2 | P25787 | 7/20 | 0.98 |
| ▸ | PSMA3 | P25788 | 7/20 | 0.98 |
| ▸ | PSMA4 | P25789 | 7/20 | 0.98 |
| ▸ | PSMA5 | P28066 | 7/20 | 0.98 |
| ▸ | PSMB4 | P28070 | 7/20 | 0.98 |
| ▸ | PSMB3 | P49720 | 7/20 | 0.98 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.98 |
| ▸ | PSMA6 | P60900 | 7/20 | 0.98 |
| ▸ | PSMA8 | Q8TAA3 | 7/20 | 0.98 |
| ▸ | PSMB7 | Q99436 | 7/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bortezomib SCHEMBL685473 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL30316729 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL8049740 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL8099424 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL192129 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL8035134 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL466239 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL29377226 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL3676 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Bortezomib SCHEMBL8036967 | 0.99 | PSMB5 (1.00) | PSMB5LONP1PSMB8PSMB9PSMB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667654-B2 | Process for the preparation of boronic acid esters | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2023-06-06 | — | — | US | disclosed |
| US-11667654-B2 | Process for the preparation of boronic acid esters | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2023-06-06 | — | — | US | disclosed |
| US-20200031850-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BORONIC ACID ESTERS | FRESENIUS KABI ONCOLOGY LIMITED (IN) | 2020-01-30 | — | — | US | disclosed |
| US-9421237-B2 | Tripeptide boronic acid or boronic ester, preparative method and use thereof | PEKING UNIVERSITY (CN) | 2016-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667654-B2 | Process for the preparation of boronic acid esters | PBRM1, BET1, MALT1 | PSMB5 275/4885LONP1 1519/4885PSMB8 1052/4885 |
| US-20200031850-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BORONIC ACID ESTERS | BET1, PBRM1, BTD | PSMB5 163/4885LONP1 1362/4885PSMB8 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.