SCHEMBL18025347

CC1C(O)[C@H](O[C@@H]2OC(CO[C@]3(C(=O)NCCNC(=O)OC(C)(C)C)C[C@@H](O)[C@@H](N)C([C@H](O)C(O)CO)O3)[C@H](O)C(O)[C@@H]2O)[C@H](CO)O[C@H]1O[C@@H]1C(O)[C@H](O)C(CO)O[C@@H]1OCC1O[C@@H](O[C@@H]2C(CO)O[C@@H](O[C@@H]3C(CO)O[C@@H](NC(=O)CBr)C(C)C3O)[C@@H](C)C2O)C(O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)C(O)C2O[C@@H]2OC(CO)[C@@H](O[C@@H]3OC(CO[C@]4(C(=O)NCCNC(=O)OC(C)(C)C)C[C@@H](O)[C@@H](N)C([C@H](O)C(O)CO)O4)[C@H](O)C(O)[C@@H]3O)C(O)[C@@H]2C)[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	SIGLEC7	Q9Y286	6/20	0.41

▸	CD209	Q9NNX6	1/20	0.40

▸	MAG	P20916	9/20	0.39

▸	SELP	P16109	1/20	0.35

▸	SELE	P16581	2/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18333481	1.00	SIGLEC7 (0.41)	SIGLEC7CD209MAGSELPSELE
SCHEMBL16348269	1.00	SIGLEC7 (0.41)	SIGLEC7CD209MAGSELPSELE
SCHEMBL18333618	0.92	SIGLEC7 (0.43)	SIGLEC7CD209MAGSELPSELE
SCHEMBL16190425	0.91	SIGLEC7 (0.44)	SIGLEC7CD209MAGSELPSELE
SCHEMBL18333657	0.91	SIGLEC7 (0.44)	SIGLEC7CD209MAGSELPSELE
SCHEMBL17199689	0.90	SIGLEC7 (0.50)	SIGLEC7CD209MAGSELPSELE
SCHEMBL17546142	0.90	SIGLEC7 (0.50)	SIGLEC7CD209MAGSELPSELE
SCHEMBL18333611	0.90	SIGLEC7 (0.50)	SIGLEC7CD209MAGSELPSELE
SCHEMBL16348275	0.87	SIGLEC7 (0.44)	SIGLEC7CD209MAGSELPSELE
SCHEMBL16190402	0.87	SIGLEC7 (0.44)	SIGLEC7CD209MAGSELPSELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9422357-B2	Glycosylated polypeptide and drug composition containing said polypeptide	GLYTECH, INC. (JP)	2016-08-23	—	—	US	disclosed