Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968527 | 0.85 | CDYL (0.50) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL18025745 | 0.84 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL16641809 | 0.82 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13431421 | 0.81 | BRD4 (0.51) | PDE4APDE4BPDE4CPDE4DDDB1 | |
| SCHEMBL18025771 | 0.81 | MAPT (0.49) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL6385829 | 0.80 | DDB1 (0.55) | DDB1CRBNKDM4EGAAMEN1 | |
| SCHEMBL31728057 | 0.78 | IDO1 (0.51) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL2828597 | 0.78 | IDO1 (0.51) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL6930683 | 0.78 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL16634786 | 0.78 | MAPT (0.49) | PDE4APDE4BPDE4CPDE4DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016133217-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE OXINDOLE COMPOUND AND TRIAZOLIUM SALT USED THEREIN AS CATALYST | 国立大学法人名古屋大学 | 2016-08-25 | — | — | WO | disclosed |