Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.75 |
| ▸ | CCR3 | P51677 | 20/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180206 | 0.93 | HRH1 (0.87) | HRH1CCR3KCNH2 | |
| SCHEMBL180307 | 0.93 | HRH1 (0.87) | HRH1CCR3KCNH2 | |
| SCHEMBL180352 | 0.92 | HRH1 (0.86) | HRH1CCR3KCNH2 | |
| SCHEMBL180015 | 0.90 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL180014 | 0.90 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL4157116 | 0.86 | HRH1 (0.74) | HRH1CCR3KCNH2 | |
| SCHEMBL14110548 | 0.86 | HRH1 (0.65) | HRH1CCR3KCNH2 | |
| SCHEMBL179973 | 0.86 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180077 | 0.86 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL4213295 | 0.85 | HRH1 (0.63) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402316-A1 | Piperidine derivatives | AstraZeneca AB (Publ) (SE) | 2012-01-04 | — | — | EP | disclosed |