Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332844 | 0.88 | CA12 (0.54) | CA12CA14CA2CA7CA1 | |
| SCHEMBL19808505 | 0.85 | CA12 (0.71) | CA12CA14CA2CA7CA1 | |
| SCHEMBL20646495 | 0.83 | CA12 (0.63) | CA12CA14CA2CA7CA1 | |
| SCHEMBL4442641 | 0.83 | CA12 (0.73) | CA12CA14CA2CA7CA1 | |
| SCHEMBL1145926 | 0.83 | CA12 (0.63) | CA12CA14CA2CA7CA1 | |
| SCHEMBL19004206 | 0.81 | CA12 (0.61) | CA12CA14CA2CA7CA1 | |
| SCHEMBL19925453 | 0.81 | CA12 (0.61) | CA12CA14CA2CA7CA1 | |
| SCHEMBL17233254 | 0.81 | CA12 (0.61) | CA12CA14CA2CA7CA1 | |
| SCHEMBL18756420 | 0.81 | CA12 (0.61) | CA12CA14CA2CA7CA1 | |
| SCHEMBL23762491 | 0.80 | CA12 (0.59) | CA12CA14CA2CA7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016131380-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO.,LTD. (CN) | 2016-08-25 | — | — | WO | disclosed |