Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005531 | 0.88 | KDM4E (0.35) | MEN1KMT2ALMNACHRM1CETP | |
| SCHEMBL19899801 | 0.88 | NPY5R (0.36) | MEN1KMT2ALMNACHRM1CETP | |
| SCHEMBL19900131 | 0.88 | NPY5R (0.36) | MEN1KMT2ALMNACHRM1CETP | |
| SCHEMBL18005415 | 0.85 | KCNQ3 (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL18005359 | 0.84 | SMN1; SMN2 (0.35) | MEN1KMT2ALMNACHRM1SMN1; SMN2 | |
| SCHEMBL18005432 | 0.84 | CNR1 (0.32) | MEN1KMT2ALMNACHRM1KDM4E | |
| SCHEMBL22509220 | 0.84 | SMN1; SMN2 (0.35) | MEN1KMT2ALMNACHRM1SMN1; SMN2 | |
| SCHEMBL18005358 | 0.80 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL19900340 | 0.80 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL18005522 | 0.77 | MEN1 (0.32) | MEN1KMT2ALMNACHRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016133959-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2016-08-25 | — | — | WO | disclosed |