SCHEMBL180306

SCHEMBL180306

Cc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 2/20 0.41
ALDH1A1 P00352 1/20 0.41
AHR P35869 2/20 0.39
TDP1 Q9NUW8 1/20 0.37
CES1 P23141 1/20 0.35
PTGS2 P35354 3/20 0.35
CHRM1 P11229 2/20 0.35
TBXA2R P21731 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
AKR1B10 O60218 1/20 0.35
ABCB11 O95342 1/20 0.35
TTR P02766 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
FABP2 P12104 1/20 0.35
RXRA P19793 1/20 0.35
NR4A1 P22736 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370015 1.00 CYP3A4 (0.46) CYP3A4MAPK1LMNAALDH1A1AHR
SCHEMBL29039830 0.97 CYP3A4 (0.43) CYP3A4MAPK1LMNAALDH1A1AHR
Methyl Alcohol SCHEMBL28788628 0.94 CYP3A4 (0.48) CYP3A4MAPK1LMNAALDH1A1AHR
SCHEMBL29086640 0.89 CYP3A4 (0.39) CYP3A4MAPK1LMNAALDH1A1AHR
SCHEMBL29403294 0.87 CYP3A4 (0.41) CYP3A4MAPK1LMNAALDH1A1TDP1
SCHEMBL477584 0.87 CYP3A4 (0.41) CYP3A4MAPK1LMNAALDH1A1TDP1
SCHEMBL11393560 0.85 TSHR (0.39) CYP3A4MAPK1LMNAALDH1A1PTGS2
Water SCHEMBL28514557 0.83 CYP3A4 (0.39) CYP3A4MAPK1LMNAALDH1A1TDP1
Fluorobenzene SCHEMBL29088471 0.82 MAPK1 (0.38) CYP3A4MAPK1LMNAALDH1A1PTGS2
Resorcinol SCHEMBL29208135 0.80 CYP3A4 (0.48) CYP3A4MAPK1LMNAALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2494 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122042872-A Separation determination of ibutinib SM based on gas chromatography3And method for impurity thereof 重庆华邦制药有限公司 2026-05-15 CN claimed
US-20250198641-A1 INDOOR AIR CLEANING SYSTEM MICROJET TECHNOLOGY CO., LTD. (TW) 2025-06-19 US claimed
EP-4571207-A1 INDOOR AIR CLEANING SYSTEM Microjet Technology Co., Ltd. (TW) 2025-06-18 EP claimed
CN-120160227-A Indoor air cleaning system 研能科技股份有限公司 2025-06-17 CN claimed
CN-120136700-A Synthesis method of L-acetoxy propionyl chloride 连云港百裕生物科技有限公司 2025-06-13 CN claimed
CN-120081672-A Silicon carbide ceramic product and preparation process thereof 黄山昊宇机电科技有限公司 2025-06-03 CN claimed
CN-120058512-A Synthesis method of acetoxyacetyl chloride 连云港百裕生物科技有限公司 2025-05-30 CN claimed
CN-120049017-A Org/ZnSO4Electrolyte, preparation method thereof and application of electrolyte in secondary battery 同济大学 2025-05-27 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-119971906-A Gas-phase feed distributor, gas-phase reaction equipment, application of gas-phase feed distributor and method for preparing nitrile compounds by ammoxidation 中国石油化工股份有限公司 2025-05-13 CN claimed
US-5410003-A Strain hardening properties; elastomeric copolymers; using modified supported vanadium based catalyst with alkylaluminum halide cocatalyst and promoter UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-04-25 US claimed
EP-0632064-A1 Ethylene/propylene copolymer rubbers UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-01-04 EP claimed
US-5332793-A Catalyst of vanadium halide, Lewis base, boron halide and alkylaluminum halide cocatalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-07-26 US claimed
EP-0589224-A1 method for forming a net-like material from a thermoplastic film KIMBERLY-CLARK CORPORATION (US) 1994-03-30 EP claimed
US-5136110-A Reacting phenol with suitable aromatic halogen compounds; recovering triaryl bisphenols THE DOW CHEMICAL COMPANY (US) 1992-08-04 US claimed
EP-0448347-A2 Pigment composition NIPPON PAINT CO., LTD. (JP) 1991-09-25 EP claimed
US-4822928-A Process for producing 2,5-dichlorotoluene KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-04-18 US claimed
US-4633026-A DEHYDROHALOGENATION OF RING-HALOGENATED ALPHA- OR BETA-BROMOETHYL BENZENES WITH STRONG BASE, POLYOXYETHYLENE GLYCOL CATALYST, AMINE POLYMERIZATION INHIBITOR ETHYL CORPORATION (US) 1986-12-30 US claimed
US-4361670-A REPAIR OF ROADWAYS USING A METALLIC SALT AS PROMOTER OF CURING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1982-11-30 US claimed
US-3992275-A Low gloss ultraviolet curable coatings utilizing α,α,α-trichlorotoluene as a photoinitiator CELANESE CORPORATION (US) 1976-11-16 US claimed