SCHEMBL180320

SCHEMBL180320

C=CCO[Si](O)(O)OCC=C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28029924 0.87 MEN1 (0.34) TSHRMEN1POLBKMT2A
SCHEMBL7718064 0.84
SCHEMBL27850371 0.84
SCHEMBL27985429 0.84
SCHEMBL8537271 0.81 TSHR (0.32) TSHRMEN1POLBKMT2ACA1
SCHEMBL36809 0.81
SCHEMBL4544256 0.81 TSHR (0.32) TSHRMEN1POLBKMT2ACA1
SCHEMBL27709395 0.80 TSHR (0.38) TSHRMEN1POLBKMT2A
SCHEMBL2989321 0.80
SCHEMBL544220 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2633120-A1 PAPERMAKING AND PRODUCTS MADE THEREBY WITH IONIC CROSSLINKED POLYMERIC MICROPARTICLE Buckman Laboratories International, Inc (US) 2013-09-04 EP claimed
US-8480853-B2 Papermaking and products made thereby with ionic crosslinked polymeric microparticle BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2013-07-09 US claimed
WO-2012058258-A1 PAPERMAKING AND PRODUCTS MADE THEREBY WITH IONIC CROSSLINKED POLYMERIC MICROPARTICLE BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2012-05-03 WO claimed
US-20120103549-A1 Papermaking And Products Made Thereby With Ionic Crosslinked Polymeric Microparticle BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2012-05-03 US claimed
CN-102015293-A Water-based barrier coating compositions MEADWESTVACO CORP 2011-04-13 CN claimed
EP-2271491-A1 WATER-BASED BARRIER COATING COMPOSITIONS MeadWestvaco Corporation (US) 2011-01-12 EP claimed
WO-2009134538-A1 WATER-BASED BARRIER COATING COMPOSITIONS MEADWESTVACO CORPORATION (US) 2009-11-05 WO claimed
CN-100354314-C Emulsion polymerization process comprising lightly modified clay and compositions containing same ROHM & HAAS (US) 2007-12-12 CN claimed
US-7259203-B2 Aqueous nanocomposite dispersions: processes, compositions, and uses thereof ROHM AND HAAS COMPANY 2007-08-21 US claimed
CN-1331893-C Aqueous nanocomposite dispersions, method, composition and use thereof ROHM & HAAS (US) 2007-08-15 CN claimed
WO-2002055563-A2 METHODS AND COMPOSITIONS INVOLVING POLAR MONOMERS AND MULTIVALENT CATIONS ROHM AND HAAS COMPANY (US) 2002-07-18 WO claimed
US-20020086908-A1 Aqueous nanocomposite dispersions: processes, compositions, and uses thereof ROHM AND HAAS COMPANY 2002-07-04 US claimed
US-20020058739-A1 Hydrophobically modified clay polymer nanocomposites ROHM AND HAAS COMPANY 2002-05-16 US claimed
US-20020055580-A1 High acid aqueous nanocomposite dispersions ROHM AND HAAS COMPANY 2002-05-09 US claimed
US-20020055581-A1 Emulsion polymerization methods involving lightly modified clay and compositions comprising same ROHM AND HAAS COMPANY 2002-05-09 US claimed
US-20020055599-A1 Water soluble cation used to form a complex in situ with a portion of the polar monomer prior to and/or during polymerization ROHM AND HAAS COMPANY 2002-05-09 US claimed
WO-2002024758-A2 EMULSION POLYMERIZATION METHODS INVOLVING LIGHTLY MODIFIED CLAY AND COMPOSITIONS COMPRISING SAME ROHM AND HAAS COMPANY (US) 2002-03-28 WO claimed
WO-2002024760-A2 AQUEOUS NANOCOMPOSITE DISPERSIONS: PROCESSES, COMPOSITIONS, AND USES THEREOF ROHM AND HAAS COMPANY (US) 2002-03-28 WO claimed
WO-2002024756-A2 HYDROPHOBICALLY MODIFIED CLAY POLYMER NANOCOMPOSITES ROHM AND HAAS COMPANY (US) 2002-03-28 WO claimed
WO-2002024757-A2 HIGH ACID AQUEOUS NANOCOMPOSITE DISPERSIONS ROHM AND HAAS COMPANY (US) 2002-03-28 WO claimed