SCHEMBL180335

SCHEMBL180335

CCCCc1ccc(-c2ccc(CC(N)C(=O)O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.59
SLC7A5 Q01650 3/20 0.56
PTGS1 P23219 2/20 0.54
ALPI P09923 1/20 0.54
PKM P14618 1/20 0.54
XIAP P98170 1/20 0.54
KIF11 P52732 1/20 0.53
ALDH1A1 P00352 3/20 0.53
RARA P10276 2/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
MTOR P42345 1/20 0.53
KMT2A Q03164 1/20 0.53
HSD17B10 Q99714 2/20 0.51
HPGD P15428 1/20 0.51
S1PR2 O95136 2/20 0.48
S1PR1 P21453 2/20 0.48
TPH1 P17752 1/20 0.48
GRB2 P62993 1/20 0.48
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2779653 0.95 SLC7A5 (0.61) RARBSLC7A5PTGS1ALPIPKM
SCHEMBL2779651 0.95 SLC7A5 (0.61) RARBSLC7A5PTGS1ALPIPKM
SCHEMBL6771201 0.95 SLC7A5 (0.61) RARBSLC7A5PTGS1ALPIPKM
SCHEMBL169161 0.90 SLC7A5 (0.59) RARBSLC7A5PTGS1ALPIPKM
SCHEMBL1993787 0.90 SLC7A5 (0.59) RARBSLC7A5PTGS1ALPIPKM
SCHEMBL28381546 0.89 S1PR2 (0.60) RARBSLC7A5PTGS1ALPIPKM
SCHEMBL28653399 0.85 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2496326 0.85 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL837014 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL156189 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332217-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2025-10-30 US claimed
US-12239686-B2 Immune checkpoint inhibitor combinations LYTIX BIOPHARMA AS (NO) 2025-03-04 US claimed
US-20240293506-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2024-09-05 US claimed
US-20230201305-A9 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2023-06-29 US claimed
US-20210401933-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2021-12-30 US claimed
EP-3229823-B1 CHEMOTHERAPEUTIC COMBINATIONS OF CATIONIC ANTIMICROBIAL PEPTIDES AND CHEMOTHERAPEUTICS LYTIX BIOPHARMA AS (NO) 2021-10-20 EP claimed
US-11123398-B2 Chemotherapeutic combinations of cationic antimicrobial peptides and chemotherapeutics LYTIX BIOPHARMA AS (NO) 2021-09-21 US claimed
US-11083774-B2 Immune checkpoint inhibitor combinations LYTIX BIOPHARMA AS (NO) 2021-08-10 US claimed
EP-2402364-B1 A nonapeptide with anti-tumour activity LYTIX BIOPHARMA AS (NO) 2019-04-03 EP claimed
US-20180264079-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2018-09-20 US claimed
US-20170340696-A1 CHEMOTHERAPEUTIC COMBINATIONS OF CATIONIC ANTIMICROBIAL PEPTIDES AND CHEMOTHERAPEUTICS LYTIX BIOPHARMA AS (NO) 2017-11-30 US claimed
EP-3229823-A1 CHEMOTHERAPEUTIC COMBINATIONS OF CATIONIC ANTIMICROBIAL PEPTIDES AND CHEMOTHERAPEUTICS Lytix Biopharma AS (NO) 2017-10-18 EP claimed
EP-3230318-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS Lytix Biopharma AS (NO) 2017-10-18 EP claimed
US-20160176923-A1 NONAPEPTIDE WITH ANTI-TUMOUR ACTIVITY VERRICA PHARMACEUTICALS INC. 2016-06-23 US claimed
WO-2016091490-A1 CHEMOTHERAPEUTIC COMBINATIONS OF CATIONIC ANTIMICROBIAL PEPTIDES AND CHEMOTHERAPEUTICS LYTIX BIOPHARMA AS (NO) 2016-06-16 WO claimed
WO-2016091487-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2016-06-16 WO claimed
EP-2402364-A2 A nonapeptide with anti-tumour activity Lytix Biopharma AS (NO) 2012-01-04 EP claimed
US-20110318364-A1 NONAPEPTIDE WITH ANTI-TUMOUR ACTIVITY LYTIX BIOPHARMA AS (NO) 2011-12-29 US claimed
US-20250332217-A1 IMMUNE CHECKPOINT INHIBITOR COMBINATIONS LYTIX BIOPHARMA AS (NO) 2025-10-30 US disclosed
WO-2010060497-A1 A NONAPEPTIDE WITH ANTI-TUMOUR ACTIVITY LYTIX BIOPHARMA AS (NO) 2010-06-03 WO disclosed