Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.75 |
| ▸ | PIK3C2B | O00750 | 10/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL685506 | 0.93 | PIK3CD (0.75) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL680957 | 0.86 | PIK3CD (0.88) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL681698 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL681993 | 0.82 | PIK3C2B (1.00) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL681061 | 0.80 | PIK3C2B (1.00) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL681700 | 0.79 | PIK3CD (1.00) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL680974 | 0.78 | PIK3CG (1.00) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL15892695 | 0.78 | PIK3C2B (0.80) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL680909 | 0.77 | PIK3CD (0.84) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB | |
| SCHEMBL681716 | 0.77 | PIK3C2B (1.00) | PIK3CDPIK3C2BPIK3CGPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346508-B1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE LLC (US) | 2016-08-24 | — | — | EP | disclosed |